What is Profhilo Structura?
9 February 2026 · 5 min read
ProfhiloProfhilo Structura is a newer, thicker formulation of Profhilo designed to address skin laxity and provide mild structural support alongside hydration. It targets the cheeks and jawline specifically, with results building over four to six weeks after a two-session protocol.
If you've heard of Profhilo and wondered what Profhilo Structura is, the short answer is that they're related but different. Same brand, same underlying technology, different purpose. Structura was developed to address something standard Profhilo doesn't fully cover: areas where the skin has started to sag or lose structural support, not just hydration and quality.
How is Profhilo Structura different from standard Profhilo?
Standard Profhilo is a highly fluid injectable that spreads widely through the tissue, intensely hydrating the skin and stimulating collagen and elastin broadly across the face. Its primary effect is on skin quality: hydration, firmness, and the overall bio-remodelling of the tissue.
Profhilo Structura uses the same hyaluronic acid (HA) technology but in a thicker, more cohesive formulation. Because it doesn't spread as freely, it stays more localised where it's injected, providing a mild scaffolding effect in addition to the skin quality improvement.
It's injected at different points too. Standard Profhilo uses the BAP (Bio Aesthetic Points) technique across the face. Structura is placed at specific points in the cheek and jawline area, where the structural benefit is most relevant.
The two products are designed to complement each other. Many practitioners use both in the same treatment plan: Structura to address laxity and provide mild lift, standard Profhilo to improve overall skin quality across the face.
What does Profhilo Structura treat?
Structura is specifically designed for the mid-face and lower face, where skin laxity typically begins to show. The main concerns it addresses are:
- Sagging or flattening of the cheeks
- Loss of definition along the jawline
- Early jowling where the lower face begins to lose its contour
- The overall deflated or tired appearance that comes with mid-face volume and structural loss
It's positioned between standard Profhilo, which improves skin quality without structural change, and traditional dermal fillers, which add direct volume. Structura provides mild support and lift without the more pronounced volumising effect of a conventional filler.
Who is Profhilo Structura for?
Structura is best suited to people who are noticing early to moderate sagging in the cheek or jawline area and want to address it without significant volume addition. Good candidates are typically in their late 30s to 50s, with skin that has begun to lose structure but hasn't reached the point where surgery or significant volume replacement is the only realistic option.
It's also a good option for people who have tried standard Profhilo and want to build on those results with something that addresses the structural element as well as skin quality.
It's not the right treatment for significant volume loss or pronounced sagging, where biostimulators like Sculptra, structural fillers, or lifting procedures like HIFU or Morpheus8 would be more appropriate.
Profhilo Structura before and after: what to expect
Results from Profhilo Structura tend to show more visible improvement in the mid-face and jawline definition than standard Profhilo before and afters. The change is still subtle by the standards of more volumising treatments, but the structural element produces a slightly more defined result.
What people typically notice:
- Cheeks that look slightly more supported and lifted
- A more defined transition from cheek to jawline
- A reduction in the flat or deflated appearance that early mid-face laxity creates
- An overall improvement in skin quality alongside the structural change
The timeline mirrors standard Profhilo. Results develop gradually over four to six weeks after each session, with the full effect visible four to six weeks after the second session.
What to expect from treatment
The protocol for Profhilo Structura is two sessions, four weeks apart, mirroring standard Profhilo. Sessions take around 30 minutes. Injection points are placed specifically in the cheek and jawline area rather than distributed across the full face.
Some mild swelling and small bumps at injection sites are normal immediately after and settle within 24 to 48 hours. Most people return to normal activities the same day.
Results last around six to nine months, similar to standard Profhilo, after which the stimulated collagen and elastin gradually breaks down and a top-up session is recommended.
How much does Profhilo Structura cost?
Profhilo Structura typically costs between £300 and £500 per session in the UK, putting a full two-session course at £600 to £1,000. It's often priced slightly higher than standard Profhilo due to the newer formulation. Prices vary by clinic and location.
When used alongside standard Profhilo in the same treatment plan, some clinics offer combined pricing. It's worth asking at consultation what the practitioner recommends and how they would price a combined approach.
Frequently asked questions
What is the difference between Profhilo and Profhilo Structura?
Standard Profhilo is a fluid injectable that spreads widely to hydrate and bio-remodel the skin broadly. Profhilo Structura is a thicker formulation that stays more localised, providing mild structural support and lift in the cheeks and jawline alongside the skin quality improvement. They're designed to be used together.
How long does Profhilo Structura last?
Results typically last six to nine months, similar to standard Profhilo. A single top-up session at this point maintains results without needing to repeat the full two-session protocol.
Can Profhilo Structura replace fillers?
Not entirely. Structura provides mild structural support and is appropriate for early to moderate laxity. For significant volume loss or pronounced sagging, traditional fillers or biostimulators like Sculptra or Radiesse provide more meaningful correction.
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